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Table 2 Comparisons of neural responses between patients with PD and healthy participants during acupuncture stimulation

From: Acupuncture on GB34 activates the precentral gyrus and prefrontal cortex in Parkinson’s disease

 

Healthy > Patients with PD

Healthy < Patients with PD

Cerebral area

Coordinates anatomical location

Statistical values

Coordinates anatomical location

Statistical values

Brain region

L/R

Brodmann area

x

y

z

t value

x

y

z

t value

Frontal lobe

          

Middle frontal gyrus

Right

6

21

5

48

3.19

-

-

-

-

Inferior frontal gyrus

Left

45/47

-

-

-

-

-32

29

-1

4.47

Precentral gyrus

Left

4/6

-

-

-

-

-28

-29

57

5.36

Parietal lobe

          

Precuneus

Left

7

-

-

-

-

-26

-59

36

5.37

Postcentral gyrus

Left

2/3/40

-

-

-

-

-46

-19

43

5.36

Temporal lobe

          

Hippocampus

Right

 

32

-35

0

4.63

-

-

-

-

Superior temporal gyrus

Left

22/38/41

-

-

-

-

-51

-22

3

4.69

Middle temporal gyrus

Left

37

-

-

-

-

-40

-60

5

4.39

Inferior temporal gyrus

Left

19

-

-

-

-

-44

-52

2

3.99

Sub-lobar

          

Caudate body

Right

 

15

-29

27

5.04

-

-

-

-

Caudate tail

Right

 

25

-35

21

3.96

-

-

-

-

Putamen

Right

 

25

3

16

3.98

-

-

-

-

Insula

Right

13

30

-15

27

3.41

-

-

-

-

Caudate body

Left

 

-16

-23

27

4.11

-

-

-

-

Caudate tail

Left

 

-18

-30

26

3.92

-

-

-

-

Thalamus

Left

 

1

-19

4

3.88

-

-

-

-

Insula

Left

13

-

-

-

-

-45

-5

5

4.81

Claustrum

Left

 

-

-

-

-

-31

19

0

4.17

Limbic lobe

          

Cingulate gyrus

Right

23/24/31/32

23

-13

39

4.33

-

-

-

-

Occipital lobe

          

Precuneus

Left

31

-

-

-

-

-27

-71

21

4.34

Fusiform gyrus

Left

19

-

-

-

-

-21

-66

-8

3.99

Cluster size

  

9920

   

18776

   
  1. The table describes the location of the peak voxel and the corresponding brain regions and Brodmann areas comprised by the cluster. Results are reported if cluster level corrected P < 0.05. The voxel size is 2.4 × 2.4 × 4.5 mm. “Healthy participants > Patients with PD” indicates more activated neural responses of healthy participants compared to patients with PD. “Healthy participants < Patients with PD” indicates more activated neural responses of patients with PD compared to healthy participants (two-sample t test; with corrected cluster level P < 0.05).