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Table 1 Antimutagenic effect of fractions Darjeeling tea extract (DTE) in Salmonella strains TA98 and TA100 in preincubation tests

From: Antimutagenic and anticancer activity of Darjeeling tea in multiple test systems

DTE (μg/plate)

Mean ± SD plus S9 mix

TA 98

 

Control (100 μl of DMSO)

52 ± 12

B[a]P (50 ug/plate)

256 ± 23

B[a]P + 1

247 ± 21

B[a]P + 10

240 ± 18

B[a]P + 100

212 ± 20 **

B[a]P + 500

167 ± 16 **

B[a]P + 1000

106 ± 17 **

TA 100

 

Control (100 μl of DMSO)

138 ± 12

B[a]P (50 μg/plate)

786 ± 34

B[a]P + 1

770 ± 25

B[a]P + 10

737 ± 21

B[a]P + 100

695 ± 36 *

B[a]P + 500

512 ± 24 **

B[a]P + 1000

440 ± 37 **

  1. Each data represented as Mean ± SD of four plates. Results of each concentration of DTE plus positive mutagen benzo[a]pyrene (B[a]P) were compared with the positive mutagen treated group alone (all in presence of S9 mix) by Dunnett’s multiple comparison. *P < 0.05, **P < 0.01.