Figure 3

Effects of the pure rutin (A), hesperidin (B), quercetin (C), and quercitrin (D) on immobility time in TST. The mice were tested 60 min after they were administered (p.o.) with the vehicle (physiological saline with 2% Tween 80), 20 mg/kg fluoxetine, 0.1, 1, 2, 4, and 8 mg/kg rutin, 0.03, 0.3, 1, 2, and 4 mg/kg hesperidin, 0.01, 0.1, 0.2, 0.4, and 0.8 mg/kg quercetin, and 0.01, 0.1, 0.2, 0.4, and 0.8 mg/kg quercitrin. Data are expressed as mean ± S.E.M. (n = 10). Data were analyzed using one-way ANOVA for multiple comparisons, followed by post hoc Student–Newman–Keuls test. *p < 0.05, **p < 0.01, and ***p < 0.001 compared with the control group (vehicle); #p < 0.05, ##p < 0.01, and ###p < 0.001 compared with the positive reference group (fluoxetine).