Figure 5From: Pain and sensory detection threshold response to acupuncture is modulated by coping strategy and acupuncture sensation Neurobiological integrative model. Our results can be integrated with existing animal models for PAG response to escapable and in-escapable stressors [32]. The psychological coping condition is integrated with physical stimulation intensity, modulating physiological outcomes via different PAG subregions. Specifically, L/DL-PAG activity mediates active coping strategies to impart sympathetic mediated non-opioidergic analgesia, while VL-PAG activity mediates passive coping strategies to impart parasympathetic mediated, opioidergic analgesia.Back to article page