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Figure 5 | BMC Complementary and Alternative Medicine

Figure 5

From: Pain and sensory detection threshold response to acupuncture is modulated by coping strategy and acupuncture sensation

Figure 5

Neurobiological integrative model. Our results can be integrated with existing animal models for PAG response to escapable and in-escapable stressors [32]. The psychological coping condition is integrated with physical stimulation intensity, modulating physiological outcomes via different PAG subregions. Specifically, L/DL-PAG activity mediates active coping strategies to impart sympathetic mediated non-opioidergic analgesia, while VL-PAG activity mediates passive coping strategies to impart parasympathetic mediated, opioidergic analgesia.

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