TY - JOUR AU - Saleh, Farid AU - Raghupathy, Raj AU - Asfar, Sami AU - Oteifa, Medhat AU - Al-Saleh, Noha PY - 2014 DA - 2014/08/30 TI - Analysis of the effect of the active compound of green tea (EGCG) on the proliferation of peripheral blood mononuclear cells JO - BMC Complementary and Alternative Medicine SP - 322 VL - 14 IS - 1 AB - Cancer immunotherapy requires proper manipulation of the immune system, lymphocytes in particular, in order to identify and destroy the cancer cells as non-self. In this study we investigated the effect of the flavonoid present in green tea, namely epigallocatechin-3-gallate (EGCG), on the proliferation of, and IFN-γ production by, peripheral blood mononuclear cells (PBMC) from breast cancer patients stimulated with a mitogen, anti-CD3 and the common breast cancer peptides Her-2/neu, and p53. SN - 1472-6882 UR - https://doi.org/10.1186/1472-6882-14-322 DO - 10.1186/1472-6882-14-322 ID - Saleh2014 ER -