Evaluation of antimalarial activity of leaves of Acokanthera schimperi and Croton macrostachyus against Plasmodium berghei in Swiss albino mice

Table 6 Suppressive effect of aqueous extract of Croton macrostachyus and mean survival time

Group	Dose (mg/kg)	Antimalarial activities on Day-4 post infection		Mean survival time in days
Group	Dose (mg/kg)	% Parasitaemia ± SEM	% Suppression	Mean survival time in days
1	Distilled water (1 mL)	46.89 ± 1.03	0.00	7.20 ± 0.20
2	200	34.24 ± 5.16	26.14	7.40 ± 0.98^b
3	400	32.60 ± 4.50	30.50	7.80 ± 0.37^b
4	600	23.20 ± 7.87	50.53	7.40 ± 0.60^b
5	Chloroquine (25)	0.00	100.00	11.75 ± 0.48*

% parasitaemia and mean survival time results presented as mean ± SD; n = 5; * = values are significantly different from that of the negative control; values with Superscript b- are not significantly different from the negative control (P > 0.05).

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