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Table 5 Suppressive effect of methanol extracts of C roton macrostachyus and mean survival time

From: Evaluation of antimalarial activity of leaves of Acokanthera schimperi and Croton macrostachyus against Plasmodium berghei in Swiss albino mice

Group

Dose (mg/kg)

Antimalarial activities on Day-4 post infection

Mean survival time in days

% Parasitaemia ± SEM

% Suppression

1

Distilled water (1 mL)

46.86 ± 1.03

0.00

7.20 ± 0.37

2

200

38.56 ± 3.07

21.06

7.80 ± 0.58b

3

400

33.88 ± 5.75

27.72

7.40 ± 0.98b

4

600

30.80 ± 5.56

34.33

7.40 ± 0.93b

5

Chloroquine (25)

0.00

100.00

11.75 ± 0.48*

  1. % parasitaemia and mean survival time results presented as mean ± SD; n = 5; * = values are significantly different from that of the negative control; values with Superscript b- are not significantly different from that of the negative control (P > 0.05).