Figure 5

Effect of AST on splenic mRNA expression of RORγt, T-bet, and Foxp3 of EAE mice. A) AST inhibited RORγt mRNA expression. B) AST increased T-bet mRNA expression. C) AST elevated Foxp3 mRNA expression. All data are presented as mean±standard error of the mean. The dose of AST used was 50 mg/kg/day. n = 5 in each group. ^*p < 0.05; ^**p < 0.01; ^***p < 0.001 vs EAE group.