Figure 4

Effect of AST on hippocampal mRNA expression of GFAP, CD11b and iNOS in EAE mice. A) AST inhibited GFAP mRNA expression. B) AST reduced CD11b mRNA expression. C) AST prevented iNOS mRNA expression. All data are presented as mean±standard error of mean. The dose of AST used was 50 mg/kg/day. n = 5 in each group. ^*p < 0.05; ^**p < 0.01 vs EAE group.