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Table 4 Glucose adsorption capacity of insoluble fibre of CA in different concentrations of glucose

From: Anti-hyperglycemic activity of Centella asiatica is partly mediated by carbohydrase inhibition and glucose-fiber binding

Treatment Glucose bound (mmol/g)
5 mmol/l 10 mmol/l 50 mmol/l 100 mmol/l 200 mmol/l
CA 250 mg 0.03 ± 0.01a 0.91 ± 0.11a 4.88 ± 0.93a 9.23 ± 1.02a 19.43 ± 3.37a
CA 500 mg 0.06 ± 0.01b 1.87 ± 0.43b 6.78 ± 2.10b 13.89 ± 3.67b 23.88 ± 4.87b
CA 1000 mg 0.08 ± 0.02c 2.67 ± 0.61c 8.93 ± 1.98c 16.75 ± 4.12c 29.94 ± 7.50c
CMC 1000 mg 0.08 ± 0.01c 2.71 ± 0.45c 9.32 ± 2.09c 17.81 ± 3.78c 30.97 ± 6.88c
  1. Data are presented as Mean ± SEM (n = 4). Data represent the millimoles of glucose bound by each gram of the CA extract at different glucose concentrations (5-200mmol/l). Glucose bound = (glucose concentration of original solution - glucose concentration when the adsorption reached equilibrium) × volume of solution ÷ weight of dietary fibre. Mean values in the same column marked with different letters (a, b, and c) were significantly different at p < 0.05 (Values which were found to be statistically similar to the positive control were denoted as “c”; they present strong fibre binding. Values denoted by “a” and “b” were statistically different from both the positive control and themselves; these values represent non significant fibre binding) (derived from repeated-measures ANOVA and adjusted using Bonferroni correction).