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Table 4 Glucose adsorption capacity of insoluble fibre of CA in different concentrations of glucose

From: Anti-hyperglycemic activity of Centella asiatica is partly mediated by carbohydrase inhibition and glucose-fiber binding

Treatment

Glucose bound (mmol/g)

5 mmol/l

10 mmol/l

50 mmol/l

100 mmol/l

200 mmol/l

CA 250 mg

0.03 ± 0.01a

0.91 ± 0.11a

4.88 ± 0.93a

9.23 ± 1.02a

19.43 ± 3.37a

CA 500 mg

0.06 ± 0.01b

1.87 ± 0.43b

6.78 ± 2.10b

13.89 ± 3.67b

23.88 ± 4.87b

CA 1000 mg

0.08 ± 0.02c

2.67 ± 0.61c

8.93 ± 1.98c

16.75 ± 4.12c

29.94 ± 7.50c

CMC 1000 mg

0.08 ± 0.01c

2.71 ± 0.45c

9.32 ± 2.09c

17.81 ± 3.78c

30.97 ± 6.88c

  1. Data are presented as Mean ± SEM (n = 4). Data represent the millimoles of glucose bound by each gram of the CA extract at different glucose concentrations (5-200mmol/l). Glucose bound = (glucose concentration of original solution - glucose concentration when the adsorption reached equilibrium) × volume of solution ÷ weight of dietary fibre. Mean values in the same column marked with different letters (a, b, and c) were significantly different at p < 0.05 (Values which were found to be statistically similar to the positive control were denoted as “c”; they present strong fibre binding. Values denoted by “a” and “b” were statistically different from both the positive control and themselves; these values represent non significant fibre binding) (derived from repeated-measures ANOVA and adjusted using Bonferroni correction).