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Figure 8 | BMC Complementary and Alternative Medicine

Figure 8

From: Anti-hyperglycemic activity of Centella asiatica is partly mediated by carbohydrase inhibition and glucose-fiber binding

Figure 8

Effects of ethanol extract of C. asiatica (CA) on a) gastrointestinal motility (by BaSO4 traversed) and b) intestinal disaccharidase activity in type 2 diabetic rats. Rats were fasted for 20 h before the oral administration of ethanol extract of C. asiatica (250 mg/kg, 500 mg/kg, and 1000 mg/kg body weight) or water (control). Enzyme activity was determined and BaSO4 was administered at 60 min. Motility was measured over the following 15 min. Acarbose (ACB) (200 mg/Kg) and Loperamide (LPM) 5 mg/Kg) & Domperidone (DMP) (10 mg/Kg) were used as reference controls for disaccharidase activity test and gastrointestinal motility test respectively. Values are means and standard deviations represented by vertical bars (n = 12). Mean values marked with an asterisk (*) were significantly different from those of diabetic control rats (p < 0.05) (derived from repeated-measures ANOVA and adjusted using Bonferroni correction).

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