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Table 3 Effects of TAE from YHS on CYPs activity in the rat liver

From: Up-regulation on cytochromes P450 in rat mediated by total alkaloid extract from Corydalis yanhusuo

 

Dosage

The activities of CYPs (pmol · min-1 · mg-1)

Group

(mg · kg-1)

1A2

2C11

2D1

2E 1

3A1

Control

 

107.67 ± 2.36

116.00 ± 3.77

125.78 ± 9.05

299.33 ± 23.57

175.56 ± 3.35

Positive control

 

152.67 ± 2.82**

172.67 ± 2.83*

135.40 ± 1.50

930.00 ± 21.40**

351.00 ± 0.47**

TAE

6

97.78 ± 2.69

107.33 ± 0.67

120.67 ± 4.16

358.89 ± 23.65*

224.44 ± 1.92*

 

30

107.56 ± 9.46

112.22 ± 6.68

121.56 ± 6.74

503.33 ± 21.86**

246.33 ± 2.36*

 

150

155 ± 9.90**

157.11 ± 3.67*

125.78 ± 3.79

736.67 ± 14.14**

266.67 ± 5.66*

  1. Data are presented as mean ± SD of three rats. *P < 0.05, **P < 0.01, values significantly different from the control rats.