Figure 4

Relative changes in the gene expression levels of CYP3A1 and CYP 2E1 by TAE from YHS in the rat liver, kidney, lung, and intestine. Rats were treated for 14 days with TAE, phenobarbital (positive control), or 0.5% sodium carboxymethylcellulose solution (control). The mRNA levels of CYP3A1 and CYP2E1 were determined by real-time PCR with the results normalized to those of β-actin (as indicated). Data was expressed as mean ± SD triplicate measurements of five samples. *P < 0.05; **P < 0.01, response significantly increased relative to the control group.