Brewers’ rice induces apoptosis in azoxymethane-induced colon carcinogenesis in rats via suppression of cell proliferation and the Wnt signaling pathway

Table 4 TUNEL assay for brewers’ rice-treated AOM-induced colon cancer

Group no.	Treatment	Apoptotic cells (%)	Non-apoptotic cells (%)
1	Normal	4.82 ± 1.89^b	95.18 ± 1.89^b
2	AOM alone	4.08 ± 2.30^b	95.92 ± 2.30^b
3	AOM + 10% (w/w) of brewers’ rice	6.70 ± 0.99^b	93.31 ± 0.99^b
4	AOM + 20% (w/w) of brewers’ rice	20.68 ± 10.92^a	79.33 ± 10.92^a
5	AOM + 40% (w/w) of brewers’ rice	31.89 ± 5.22^a	68.12 ± 5.22^a

Each value expressed as mean ± SD of three determinations. Value in the same column with different superscript letter indicates significant difference by Tukey test (P<0.05). Administration of 20% and 40% (w/w) of brewers’ rice significantly increased in the apoptotic cells compared to the AOM-alone group (P<0.05). However, the apoptotic cells did not significantly differ between the AOM-alone group and the 10% (w/w) of brewers’ rice (P>0.05).

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