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Table 2 Tumor assessment of brewers’ rice-treated AOM-induced colon cancer

From: Brewers’ rice induces apoptosis in azoxymethane-induced colon carcinogenesis in rats via suppression of cell proliferation and the Wnt signaling pathway

Group no

Treatment

Incidence (% animals with adenoma and/or adenocarcinoma)

Tumor multiplicity (no. of tumors/rats)

  

Adenoma

Adenocarcinoma

Total

Adenoma

Adenocarcinoma

Total

1

Normal

0

0

0

0

0

0

2

AOM alone

6/6 (100%)

5/6 (83%)

6/6 (100%)

3.05 ± 0.81a

3.73 ± 0.70b

6.78 ± 0.48b

3

AOM + 10% (w/w) of brewers’ rice

4/6 (67%)

4/6 (67%)

4/6 (67%)

2.72 ± 1.73a

1.58 ± 0.56ab

4.30 ± 0.81ab

4

AOM + 20% (w/w) of brewers’ rice

3/6 (50%)

3/6 (50%)

3/6 (50%)

1.75 ± 1.10a

1.50 ± 0.80ab

3.25 ± 0.18ab

5

AOM + 40% (w/w) of brewers’ rice

2/6 (33%)

2/6 (33%)

2/6 (33%)

1.10 ± 0.59a

0.45 ± 0.38a

1.55 ± 0.46a

  1. Each value expressed as mean ± SD. Value in the same column with different superscript letter indicates significant difference by Tukey test (P<0.05).Administration of 40% (w/w) of brewers’ rice significantly reduced tumor multiplicity compared to the AOM-alone group (P<0.05). However, the colon tumor multiplicity did not significantly differ between the group fed with diets containing 10% and 20% (w/w) of brewers’ rice (P>0.05).