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Table 1 IC 50 values of A. muricata leaves extracts on five different cell lines after 72 h treatment

From: Annona muricata leaves induced apoptosis in A549 cells through mitochondrial-mediated pathway and involvement of NF-κB

Extract

IC50(μg/mL)

MCF-7

MDA-MB-231

A549

HepG2

WRL-68

Hexane

49.92 ± 2.23

38.72 ± 0.99

21.05 ± 0.42

77.92 ± 2.23

89.53 ± 3.93

Ethyl acetate

6.39 ± 0.43

11.36 ± 0.67

5.09 ± 0.41

9.3 ± 0.91

47.10 ± 1.23

Methanol

85.58 ± 3.55

> 100 *

> 100

> 100

> 100

Curcumin

7.65 ± 0.55

9.34 ± 0.76

11.32 ± 1.54

17.66 ± 1.21

54.24 ± 2.21

  1. The data represent the means ± SEM of three independent experiments.
  2. * > 100 represents the IC50 values greater than 100 μg/mL.