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Table 3 Pharmacokinetic parameters obtained alter the oral administration of 100:25 mg/kg levodopa/carbidopa in the three groups studied (initial situation; treatment with Plantago ovata husk and treatment with placebo) to 18 Parkinson patients

From: A randomised clinical trial to evaluate the effects of Plantago ovata husk in Parkinson patients: changes in levodopa pharmacokinetics and biochemical parameters

 

Initial situation

Treatment A (Plantago ovata husk)

Treatment B (Placebo)

Glucose (mg/100 ml)

105.50 ± 10.65

96.56 ± 10.62

98.06 ± 13.40

Urea (mg/100 ml)

42.96 ± 9.50

43.43 ± 11.76

45.93 ± 12.50

Creatinine (mg/100 ml)

0.89 ± 0.17

0.85 ± 0.15

0.86 ± 0.15

Tryglicerides (mg/100 ml)

94.83 ± 42.39

84.33 ± 29.28

94.11 ± 43.73

Total cholesterol (mg/100 ml)

214.39 ± 36.92

191.89 ± 27.73

209.50 ± 36.65

AST (GOT) (UI/l)

21.22 ± 4.49

19.94 ± 4.47

20.33 ± 4.34

ALT (GPT) (UI/l)

25.67 ± 8.98

25.06 ± 9.51

26.00 ± 9.29

Alkaline phosphatase (UI/l)

131.44 ± 43.91

124.00 ± 40.68

126.00 ± 44.13

GGT (UI/l)

17.06 ± 6.55

16.00 ± 6.15

19.85 ± 10.63

LDL (mg/100 ml)

135.18 ± 29.30

117.67 ± 22.23

132.32 ± 33.00

HDL (mg/100 ml)

60.17 ± 13.90

57.33 ± 15.91

58.33 ± 12.34