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Table 3 Pharmacokinetic parameters obtained alter the oral administration of 100:25 mg/kg levodopa/carbidopa in the three groups studied (initial situation; treatment with Plantago ovata husk and treatment with placebo) to 18 Parkinson patients

From: A randomised clinical trial to evaluate the effects of Plantago ovata husk in Parkinson patients: changes in levodopa pharmacokinetics and biochemical parameters

  Initial situation Treatment A (Plantago ovata husk) Treatment B (Placebo)
Glucose (mg/100 ml) 105.50 ± 10.65 96.56 ± 10.62 98.06 ± 13.40
Urea (mg/100 ml) 42.96 ± 9.50 43.43 ± 11.76 45.93 ± 12.50
Creatinine (mg/100 ml) 0.89 ± 0.17 0.85 ± 0.15 0.86 ± 0.15
Tryglicerides (mg/100 ml) 94.83 ± 42.39 84.33 ± 29.28 94.11 ± 43.73
Total cholesterol (mg/100 ml) 214.39 ± 36.92 191.89 ± 27.73 209.50 ± 36.65
AST (GOT) (UI/l) 21.22 ± 4.49 19.94 ± 4.47 20.33 ± 4.34
ALT (GPT) (UI/l) 25.67 ± 8.98 25.06 ± 9.51 26.00 ± 9.29
Alkaline phosphatase (UI/l) 131.44 ± 43.91 124.00 ± 40.68 126.00 ± 44.13
GGT (UI/l) 17.06 ± 6.55 16.00 ± 6.15 19.85 ± 10.63
LDL (mg/100 ml) 135.18 ± 29.30 117.67 ± 22.23 132.32 ± 33.00
HDL (mg/100 ml) 60.17 ± 13.90 57.33 ± 15.91 58.33 ± 12.34