Figure 4
Effect of melittin on mRNA expression of Bcl-2 and Bax in H 2 O 2 -treated SH-SY5Y cells. (A) Melittin inhibited the decrease of Bcl-2 mRNA as determined by reverse transcription-PCR. (B) Melittin blocked the increase of Bax mRNA as measured by reverse transcription-PCR. (C) Melittin caused a low Bax/Bcl-2 mRNA ratio. Data are expressed as mean ± SEM from 3 independent experiments. Bars with different letters indicate significant differences at p < 0.05.