Figure 5

Effect of curcumin on HCMV IE and UL83 antigen expressions. (I) HCMV IEA expression by Western blot. (II) Relative HCMV IEA protein levels were normalized to β-actin protein levels and expressed as percentage (%). (III) HCMV UL83A expression by Western blot. (IV) Relative HCMV UL83A protein levels were normalized to β-actin protein levels and expressed as%. A, HELF cells (control); B, HELF cells + HCMV (model); C, HELF cells + HCMV + GCV; D, HELF cells + HCMV + curcumin (high dose: 0.8 μg/ml); E, HELF cells + HCMV + curcumin (middle dose: 0.4 μg/ml); F, HELF cells + HCMV + curcumin (low dose: 0.2 μg/ml).**P < 0.01 compared with the control; ^## P < 0.01, ^# P < 0.05 compared with HCMV infection.