Skip to main content

Table 2 Antioxidant parameters of rat liver

From: Thymoquinone attenuates cisplatin-induced hepatotoxicity via nuclear factor kappa- β

 

Group 1

Group 2

Group 3

MDA, nmol/mg protein

0.52 ± 0.06

5.1 ± 0.85a

0.95 ± 0.02b

GSH, nmol/mg protein

111 ± 5.8

55.9 ± 4.6a

89.5 ± 2.1b

GST, nmol/mg protein

18.6 ± 1.5

6.29 ± 0.39a

14.76 ± 0.86b

SOD, U/mg protein

15.8 ± 1.1

9.6 ± 2.1a

14.25 ± 1.1b

CAT, U/mg protein

5.95 ± 0.5

2.41 ± 0.31a

4.56 ± 0.54b

GSH-Px, U/mg protein

4.95 ± 0.21

2.05 ± 0.12a

4.67 ± 0.65b

  1. The expressed values are mean ± S.D. of triplicate tests (n = 15).
  2. a P < 0.05 vs group1, b P < 0.05 vs group 2.
  3. The activity of the antioxidant enzymes as well as the levels of MDA and GSH in the liver homogenates of different groups.