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Table 1 Biochemical parameters of liver function tests as well as initial and final body weights of rat

From: Thymoquinone attenuates cisplatin-induced hepatotoxicity via nuclear factor kappa- β

 

Group 1

Group 2

Group 3

Initial body weight, g

210 ± 10

203 ± 12

201 ± 12

Final body weight, g

243 ± 18

172 ± 12a

225 ± 12b

ALT, U/L

29.12 ± 1.12

98.32 ± 2.3a

39.2 ± 1.3

AST, U/L

26.78 ± 1.5

90.78 ± 1.14a

48.5 ± 5.3

ALP, U/L

167.34 ± 2.32

369.12 ± 18.8a

215.3 ± 11.2b

LDH, U/L

75.67 ± 2.12

155.56 ± 2.4a

112 ± 4.2b

γGGT, U/L

59.36 ± 1.45

109.5 ± 2.43a

85 ± 3.5

t. protein, mg%

9.53 ± 0.76

6.15 ± 1.27

6.8 ± 2.1

Albumin, mg%

3.94 ± 0.98

2.4 ± 0.54a

4.65 ± 2.5b

t. Bilirubin, mg%

0.75 ± 0.05

1.6 ± 0.23a

1.1 ± 0.01b

  1. Values are expressed as mean ± S.D. of triplicate tests (n = 15).
  2. a P < 0.05 vs group1, b P < 0.05 vs group 2.
  3. The effect of TQ on the liver function parameters of different groups.