The natural triterpene 3β,6β,16β-trihydroxy-lup-20(29)-ene obtained from the flowers of Combretum leprosum induces apoptosis in MCF-7 breast cancer cells

Table 1 Saccharomyces cerevisiae strains used in this study

Strain	Genotype	Enzymatic defense lacking	Source
EG103 (SOD-WT)	MATα: leu2 Δ0 his 3-Δ1 trp1-289 ura 3-52	None	E. Gralla^a
EG118 (sod1 Δ)	Like EG103, except sod1::URA3	Cu-Zn SOD (cytosolic)	E. Gralla^a
EG110 (sod2 Δ)	Like EG103, except sod2::TRP1	Mn SOD (Mitochondrial)	E. Gralla^a
EG133 (sod1 Δsod2 Δ)	Like EG103, except sod1::URA3 and sod2::TRP1	Without SOD	E. Gralla^a
XV185-14c (WT)	MATα: ade2-2 his1-798 lys1-1 trp5-48 hom3-10 arg4-17	None	von Borstel et al. (1971)^b

^aDepartment of Chemistry and Biochemistry, University of California, Los Angeles 90024–1569, USA. ^bVon Borstel RC, Cain KT, Steinberg CM (1971) Inheritance of spontaneous mutability in yeast. Genetics 69:17–27.

ISSN: 2662-7671