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Table 2 Effect of GO2KA1 and acarbose treatment on various parameters in db/db mice

From: Effect of long-term supplementation of low molecular weight chitosan oligosaccharide (GO2KA1) on fasting blood glucose and HbA1c in db/db mice model and elucidation of mechanism of action

 

db/db mouse

 

Control

GO2KA1

Acarbose

In fasting mice

   

Glucose

496.00 ± 50.02

162.93 ± 36.93***

150.80 ± 77.0***

HbA1c

12.58 ± 1.11

5.80 ± 0.80***

5.10 ± 0.30***

Total Cholesterol

203.30 ± 46.85

130.65 ± 28.20***

180.70 ± 25.60

Triglyceride

137.91 ± 12.60

136.33 ± 6.33

123.90 ± 16.40

Cecum

0.36 ± 0.05

0.63 ± 0.18***

1.60 ± 0.40***

  1. Each point represents mean ± SD. (n = 10). *p < 0.05, **p < 0.01, and ***p < 0.001 compared to different samples at the same concentration by unpaired Student’s t-test.