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Figure 2 | BMC Complementary and Alternative Medicine

Figure 2

From: Differentiation therapy: sesamin as an effective agent in targeting cancer stem-like side population cells of human gallbladder carcinoma

Figure 2

Biological characteristics of cancer stem-like SP cells. SP cells had higher tumor-sphere formation ability than the non-SP cells under un-differentiating conditions (DMEM/F12 medium supplemented with 20 ng/mL EGF and 10 ng/mL bFGF) (A). SP cells demonstrated much higher colony formation ability (B) and invasion capacity (C). SP cells were more resistant to cisplatin (Cis) compared with non-SP cells (D and E) SP cells fraction decreased gradually under differentiating conditions (DMEM supplemented with 10% FBS) (F). *p < 0.05 vs. non-SP cells group or control group.

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