Cytotoxic effects of SCS alone and in combination with tamoxifen on MCF-10A cells. Cytotoxicity was measured at 24, 48 and 72 h of treatment with SCS (8.5 μg/ml), tamoxifen (5 and 15 μM) and their combination using the LDH assay. DMSO was used as a vehicle control. Data shown are the mean values ± SD from three independent experiments. Statistical analysis was determined using one-way ANOVA followed by post hoc Tukey multiple comparison test with *p < 0.05 and ***p < 0.001 compared to control.