Groups | Renal function parameters | ||
---|---|---|---|
Blood urea nitrogen (BUN) (mM/L) | Glycated serum protein (GSP) (μ mol/L) | Serum creatinine (μ mol/L) | |
Normal rats (untreated with dimethylsulfoxide, [DMSO]) Group 1 | 6.54 ± 0.1503 | 152.3 ± 0.5651 | 27.35 ± 0.1943 |
Diabetic control (administered with Streptozotocin (STZ) Group 2 | 13.63 ± 0.1404 | 313.9 ± 1.426 | 37.29 ± 0.1431 |
Diabetic control + (ALEx) (100 mg/kg body weight) Group 3 | 12.11 ± 0.02990ns | 285.7 ± 1.548ns | 34.54 ± 0.1297 |
Diabetic control + (ALEx) (200 mg/kg body weight) Group 4 | 10.53 ± 0.1070 | 204.1 ± 1.795 | 33.43 ± 0.1779ns |
Diabetic control + (ALEx) (300 mg/kg body weight) Group 5 | 8.48 ± 0.1101** | 181.9 ± 0.3565* | 32.29 ± 0.1512** |
Diabetic control + (ALEx) (400 mg/kg body weight) Group 6 | 7.586 ± 0.1244*** | 162.2 ± 0.6422*** | 30.24 ± 0.06719*** |
Diabetic control + Glibenclamide (1 mg/kg b wt.) Group 7 | 7.122 ± 0.03121*** | 160.8 ± 0.3589*** | 29.5 ± 0.1336 |