Groups | Oxidative stress | |||
---|---|---|---|---|
SOD (units/mg protein) | CAT (μ mol/min/mg protein) | GSH-px (μ mol/min/mg protein) | GSH (mM/100 g tissue) | |
Normal rats (untreated with dimethylsulfoxide, [DMSO]) Group 1 | 10.3 ± 0.1642 | 86.24 ± 0.7028 | 12.51 ± 0.1523 | 56.23 ± 0.5273 |
Diabetic control (administered with Streptozotocin (STZ) Group 2 | 2.67 ± 0.07218 | 25.28 ± 0.4598 | 6.274 ± 0.1402 | 24.58 ± 0.1815 |
Diabetic control + (ALEx) (100 mg/kg body weight) Group 3 | 3.794 ± 0.1306 | 26.89 ± 0.3122ns | 6.628 ± 0.08243 | 25.7 ± 0.1362 |
Diabetic control + (ALEx) (200 mg/kg body weight) Group 4 | 6.366 ± 0.01965 | 38.08 ± 0.4018 | 7.28 ± 0.01304ns | 35.69 ± 0.2022 |
Diabetic control + (ALEx) (300 mg/kg body weight) Group 5 | 7.44 ± 0.1626** | 58.61 ± 0.2086** | 9.694 ± 0.1273 | 41.36 ± 0.5254** |
Diabetic control + (ALEx) (400 mg/kg body weight) Group 6 | 9.474 ± 0.1209** | 75.88 ± 0.6258*** | 11.64 ± 0.04104*** | 52.71 ± 0.4298*** |
Diabetic control + Glibenclamide (1 mg/kg b wt.) Group 7 | 10.41 ± 0.1322 | 84.3 ± 0.5113 | 12.53 ± 0.1955 | 54.52 ± 0.3057 |