Groups | Serum lipid profile | ||||
---|---|---|---|---|---|
Total cholesterol (TC) (mg/dL) | HDL cholesterol (HDL-c) (mg/dL) | LDL cholesterol (LDL-c) | Triglycerides (TG) (mg/dL) | Hepatic glycogen (mg glucose equivalents/mg wet tissue) | |
Normal rats (untreated with dimethylsulfoxide, [DMSO]) Group 1 | 128.9 ± 0.3926 | 53.19 ± 0.4878 | 27.18 ± 0.5619 | 77.57 ± 0.5943 | 49.7 ± 0.2316 |
Diabetic control (administered with Streptozotocin (STZ) Group 2 | 273 ± 0.7544 | 14.25 ± 0.2791 | 105.81 ± 0.8731ns | 193.1 ± 1.424 | 17.21 ± 0.09793 |
Diabetic control + (ALEx) (100 mg/kg body weight) Group 3 | 201.8 ± 0.3189ns | 15.26 ± 0.1843 | 82.56 ± 0.4372** | 191.7 ± 0.4291 | 19.17 ± 0.1649 |
Diabetic control + (ALEx) (200 mg/kg body weight) Group 4 | 188.1 ± 0.4720 | 28.27 ± 0.5883 | 81.11 ± 1.201 | 161.6 ± 0.5797ns | 25.41 ± 0.4521 |
Diabetic control + (ALEx) (300 mg/kg body weight) Group 5 | 162.8 ± 0.3100** | 34.69 ± 0.5712* | 43.94 ± 0.6629 | 131.3 ± 0.4677 | 38.41 ± 0.2578* |
Diabetic control + (ALEx) (400 mg/kg body weight) Group 6 | 141.4 ± 0.4808*** | 43.74 ± 0.3495*** | 30.09 ± 0.3958*** | 93.57 ± 1.389** | 41.68 ± 0.3041*** |
Diabetic control + Glibenclamide (1 mg/kg b wt.) Group 7 | 145.7 ± 0.5246 | 48.02 ± 0.1643 | 28.51 ± 0.7293 | 81.99 ± 0.5388 | 48.05 ± 0.1163 |