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Table 6 Effect of methanol/dichloromethane extract ofAlbizzia Lebbeck Benth.. stem bark (ALEx) on lipid profile in normal & STZ induced diabetic treated rats

From: RETRACTED ARTICLE: Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on streptozotocin induced diabetic rats

Groups

Serum lipid profile

Total cholesterol (TC) (mg/dL)

HDL cholesterol (HDL-c) (mg/dL)

LDL cholesterol (LDL-c)

Triglycerides (TG) (mg/dL)

Hepatic glycogen (mg glucose equivalents/mg wet tissue)

Normal rats (untreated with dimethylsulfoxide, [DMSO]) Group 1

128.9 ± 0.3926

53.19 ± 0.4878

27.18 ± 0.5619

77.57 ± 0.5943

49.7 ± 0.2316

Diabetic control (administered with Streptozotocin (STZ) Group 2

273 ± 0.7544

14.25 ± 0.2791

105.81 ± 0.8731ns

193.1 ± 1.424

17.21 ± 0.09793

Diabetic control + (ALEx) (100 mg/kg body weight) Group 3

201.8 ± 0.3189ns

15.26 ± 0.1843

82.56 ± 0.4372**

191.7 ± 0.4291

19.17 ± 0.1649

Diabetic control + (ALEx) (200 mg/kg body weight) Group 4

188.1 ± 0.4720

28.27 ± 0.5883

81.11 ± 1.201

161.6 ± 0.5797ns

25.41 ± 0.4521

Diabetic control + (ALEx) (300 mg/kg body weight) Group 5

162.8 ± 0.3100**

34.69 ± 0.5712*

43.94 ± 0.6629

131.3 ± 0.4677

38.41 ± 0.2578*

Diabetic control + (ALEx) (400 mg/kg body weight) Group 6

141.4 ± 0.4808***

43.74 ± 0.3495***

30.09 ± 0.3958***

93.57 ± 1.389**

41.68 ± 0.3041***

Diabetic control + Glibenclamide (1 mg/kg b wt.) Group 7

145.7 ± 0.5246

48.02 ± 0.1643

28.51 ± 0.7293

81.99 ± 0.5388

48.05 ± 0.1163

  1. The data are expressed as mean ± SEM. (n = number of animals in each group = 5). The comparisons were made by one way ANOVA followed by Dunnent’s test.
  2. ns = non-significant, STZ = Streptozotocin.
  3. *p < 0.05 is considered as significant when compared to the control group (0 h).
  4. **p < 0.001 is considered as very significant when compared to the control group (0 h).
  5. ***p < 0.001 is considered as extremely significant when compared to the control group (0 h).