Groups | Biochemical Parameters of Hepatic enzymes | |||
---|---|---|---|---|
Hepatic hexokinase (units/min/mg of protein) | Gluocse-6-phosphatase (units/min/mg of protein) | Fructose 1-6-biphosphatase (units/min/mg of protein) | Glucose-6-phosphate dehydrogenase (units/min/mg of protein) | |
Normal rats (untreated with dimethylsulfoxide, [DMSO]) Group 1 | 0.214 ± 0.9152 | 0.176 ± 1.583 | 0.0282 ± 0.8437 | 0.128 ± 3.020 |
Diabetic control (administered with Streptozotocin (STZ) Group 2 | 0.112 ± 1.056 | 0.273 ± 0.6038 | 0.0596 ± 1.492 | 0.058 ± 4.576ns |
Diabetic control + (ALEx) (100 mg/kg body weight) Group 3 | 0.13 ± 0.9104ns | 0.241 ± 0.5943ns | 0.0536 ± 0.6264ns | 0.0614 ± 3.447 |
Diabetic control + (ALEx) (200 mg/kg body weight) Group 4 | 0.142 ± 0.2780 | 0.219 ± 0.3499** | 0.0496 ± 0.4148 | 0.0622 ± 3.083 |
Diabetic control + (ALEx) (300 mg/kg body weight) Group 5 | 0.17 ± 0.5145 | 0.197 ± 1.831*** | 0.0386 ± 0.7895** | 0.0892 ± 7.843 |
Diabetic control + (ALEx) (400 mg/kg body weight) Group 6 | 0.210 ± 0.8454*** | 0.181 ± 0.8955*** | 0.0298 ± 1.464 | 0.122 ± 3.408** |
Diabetic control + Glibenclamide (1 mg/kg b wt.) Group 7 | 0.212 ± 0.7552 | 0.172 ± 0.4005 | 0.0287 ± 0.8724 | 0.127 ± 1.711*** |