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Table 3 Effect of methanol/dichloromethane extract of Albizzia Lebbeck Benth . stem bark (ALEx) during 120 min (2 h) on OGTT in normal & STZ induced diabetic treated rats

From: Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on streptozotocin induced diabetic rats

Groups Time (h)
0 h 0.5 h 1 h 1.5 h 2 h
Normal rats (untreated with dimethylsulfoxide, [DMSO]) Group 1 94.03 ± 1.193 135 ± 2.159 144.5 ± 1.385 155.9 ± 1.153 164.8 ± 1.785
Diabetic control (administered with Streptozotocin (STZ) Group 2 265.7 ± 1.070 275.9 ± 1.205ns 286.4 ± 1.180ns 296.6 ± 0.9096ns 306.8 ± 0.9778
Diabetic control + (ALEx) (100 mg/kg body weight) Group 3 255 ± 1.086 265 ± 0.8882ns 273.4 ± 1.024ns 283.1 ± 1.020ns 292 ± 0.8426ns
Diabetic control + (ALEx) (200 mg/kg body weight) Group 4 245.2 ± 0.9767 254.8 ± 0.8538 263 ± 1.724** 271.8 ± 1.421 280.4 ± 1.148**
Diabetic control + (ALEx) (300 mg/kg body weight) Group 5 234.2 ± 1.263 242.3 ± 1.136** 251.6 ± 0.8199** 261.7 ± 0.9516 270.8 ± 0.6865**
Diabetic control + (ALEx) (400 mg/kg body weight) Group 6 217.1 ± 1.329*** 240.3 ± 0.4723** 250 ± 0.5276** 258 ± 0.7415 265.3 ± 0.6950***
Diabetic control + Glibenclamide (1 mg/kg b wt.) Group 7 221.9 ± 0.6154 242.2 ± 0.6026** 252.1 ± 0.7302*** 261.1 ± 0.8815 269 ± 0.5970***
  1. The data are expressed as mean ± SEM. (n = number of animals in each group = 5). The comparisons were made by one way ANOVA followed by Dunnent’s test.
  2. ns = non-significant, STZ = Streptozotocin.
  3. **p < 0.001 is considered as very significant when compared to the control group (0 h).
  4. ***p < 0.001 is considered as extremely significant when compared to the control group (0 h).