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Table 2 Effect of methanol/dichloromethane extract ofAlbizzia Lebbeck Benth.stem bark (ALEx) on plasma insulin level in normal & STZ induced diabetic treated rats

From: RETRACTED ARTICLE: Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on streptozotocin induced diabetic rats

Groups

Plasma Insulin level in μ at different time interval of experimentation

At start (On 1st day)

On 21st day

On 45th day

Normal rats (untreated with dimethylsulfoxide, [DMSO]) Group 1

18.22 ± 0.2077

17.17 ± 0.2059

16.39 ± 0.3864

Diabetic control (administered with Streptozotocin (STZ) Group 2

4.31 ± 0.1612

3.27 ± 0.1263ns

2.29 ± 0.1619ns

Diabetic control + (ALEx) (100 mg/kg body weight) Group 3

4.96 ± 0.09011

6.81 ± 0.03929ns

6.78 ± 0.1546

Diabetic control + (ALEx) (200 mg/kg body weight) Group 4

5.03 ± 0.1771

6.46 ± 0.1928

7.49 ± 0.1608

Diabetic control + (ALEx) (300 mg/kg body weight) Group 5

6.68 ± 0.1338

7.59 ± 0.1604

8.29 ± 0.1517*

Diabetic control + (ALEx) (400 mg/kg body weight) Group 6

7.79 ± 0.04665*

13.07 ± 0.2095***

15.66 ± 0.1776***

Diabetic control + Glibenclamide (1 mg/kg b wt.) Group 7

7.89 ± 0.2871

13.81 ± 0.1706***

16.64 ± 0.1518***

  1. The data are expressed as mean ± SEM. (n = number of animals in each group = 5). The comparisons were made by one way ANOVA followed by Dunnent’s test.
  2. ns = non-significant, STZ = Streptozotocin.
  3. *p < 0.05 is considered as significant when compared to the control group (0 h).
  4. ***p < 0.001 is considered as extremely significant when compared to the control group (0 h).