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Table 2 Effect of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on plasma insulin level in normal & STZ induced diabetic treated rats

From: Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on streptozotocin induced diabetic rats

Groups Plasma Insulin level in μ at different time interval of experimentation
At start (On 1st day) On 21st day On 45th day
Normal rats (untreated with dimethylsulfoxide, [DMSO]) Group 1 18.22 ± 0.2077 17.17 ± 0.2059 16.39 ± 0.3864
Diabetic control (administered with Streptozotocin (STZ) Group 2 4.31 ± 0.1612 3.27 ± 0.1263ns 2.29 ± 0.1619ns
Diabetic control + (ALEx) (100 mg/kg body weight) Group 3 4.96 ± 0.09011 6.81 ± 0.03929ns 6.78 ± 0.1546
Diabetic control + (ALEx) (200 mg/kg body weight) Group 4 5.03 ± 0.1771 6.46 ± 0.1928 7.49 ± 0.1608
Diabetic control + (ALEx) (300 mg/kg body weight) Group 5 6.68 ± 0.1338 7.59 ± 0.1604 8.29 ± 0.1517*
Diabetic control + (ALEx) (400 mg/kg body weight) Group 6 7.79 ± 0.04665* 13.07 ± 0.2095*** 15.66 ± 0.1776***
Diabetic control + Glibenclamide (1 mg/kg b wt.) Group 7 7.89 ± 0.2871 13.81 ± 0.1706*** 16.64 ± 0.1518***
  1. The data are expressed as mean ± SEM. (n = number of animals in each group = 5). The comparisons were made by one way ANOVA followed by Dunnent’s test.
  2. ns = non-significant, STZ = Streptozotocin.
  3. *p < 0.05 is considered as significant when compared to the control group (0 h).
  4. ***p < 0.001 is considered as extremely significant when compared to the control group (0 h).