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Table 1 Effect of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on blood glucose level in normal & STZ induced diabetic treated rats

From: Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on streptozotocin induced diabetic rats

Groups Blood glucose level in mg/dL at different time interval of experimentation
At start (On 1st day) On 21st day On 45th day
Normal rats (untreated with dimethylsulfoxide, [DMSO]) Group 1 83.78 ± 1.031 86.45 ± 1.003 90.00 ± 0.4292
Diabetic control (administered with Streptozotocin (STZ) Group 2 305.4 ± 2.065 317.3 ± 1.612 372.3 ± 2.233
Diabetic control + (ALEx) (100 mg/kg body weight) Group 3 295.6 ± 1.842 250.1 ± 2.338ns 208.9 ± 0.5738ns
Diabetic control + (ALEx) (200 mg/kg body weight) Group 4 288 ± 0.4932 235.4 ± 0.8799ns 155.7 ± 0.4750
Diabetic control + (ALEx) (300 mg/kg body weight) Group 5 283 ± 0.7396 200.2 ± 0.3971* 125.2 ± 1.196*
Diabetic control + (ALEx) (400 mg/kg body weight) Group 6 282 ± 0.6635** 166.1 ± 0.7504** 91.68 ± 1.451***
Diabetic control + Glibenclamide (1 mg/kg b wt.) Group 7 281.1 ± 0.7859*** 157.4 ± 1.004*** 86.74 ± 1.701***
  1. The data are expressed as mean ± SEM. (n = number of animals in each group = 5). The comparisons were made by one way ANOVA followed by Dunnent’s test.
  2. ns = non-significant, STZ = Streptozotocin.
  3. *p < 0.05 is considered as significant when compared to the control group (0 h).
  4. **p < 0.001 is considered as very significant when compared to the control group (0 h).
  5. ***p < 0.001 is considered as extremely significant when compared to the control group (0 h).