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Table 1 Effect of methanol/dichloromethane extract ofAlbizzia Lebbeck Benth.stem bark (ALEx) on blood glucose level in normal & STZ induced diabetic treated rats

From: RETRACTED ARTICLE: Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on streptozotocin induced diabetic rats

Groups

Blood glucose level in mg/dL at different time interval of experimentation

At start (On 1st day)

On 21st day

On 45th day

Normal rats (untreated with dimethylsulfoxide, [DMSO]) Group 1

83.78 ± 1.031

86.45 ± 1.003

90.00 ± 0.4292

Diabetic control (administered with Streptozotocin (STZ) Group 2

305.4 ± 2.065

317.3 ± 1.612

372.3 ± 2.233

Diabetic control + (ALEx) (100 mg/kg body weight) Group 3

295.6 ± 1.842

250.1 ± 2.338ns

208.9 ± 0.5738ns

Diabetic control + (ALEx) (200 mg/kg body weight) Group 4

288 ± 0.4932

235.4 ± 0.8799ns

155.7 ± 0.4750

Diabetic control + (ALEx) (300 mg/kg body weight) Group 5

283 ± 0.7396

200.2 ± 0.3971*

125.2 ± 1.196*

Diabetic control + (ALEx) (400 mg/kg body weight) Group 6

282 ± 0.6635**

166.1 ± 0.7504**

91.68 ± 1.451***

Diabetic control + Glibenclamide (1 mg/kg b wt.) Group 7

281.1 ± 0.7859***

157.4 ± 1.004***

86.74 ± 1.701***

  1. The data are expressed as mean ± SEM. (n = number of animals in each group = 5). The comparisons were made by one way ANOVA followed by Dunnent’s test.
  2. ns = non-significant, STZ = Streptozotocin.
  3. *p < 0.05 is considered as significant when compared to the control group (0 h).
  4. **p < 0.001 is considered as very significant when compared to the control group (0 h).
  5. ***p < 0.001 is considered as extremely significant when compared to the control group (0 h).