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Figure 2 | BMC Complementary and Alternative Medicine

Figure 2

From: Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on streptozotocin induced diabetic rats

Figure 2

Effect of Albizia Lebbeck Benth. stem bark extract (ALEx) on histological profile of pancreas in normal, STZ-induced diabetic untreated and STZ-induced diabetic treated wistar rats (Original magnification 10×, DXIT 1200 , Nikon, Japan). (i) NPALx: Heamatoxylin and eosin (H/E) stained sections of pancreas of normal control rat portraying normal islet of langerhans shown by yellow arrows. (ii) STZP: Pancreatic section of streptozotocin induced diabetic rat showing no/destroyed islet of langerhans and beta cells depicted by yellow arrows. (iii) AL100: Pancreatic section of STZ-induced diabetic rats treated with ALEx at 100 mg/kg body wt. showing small number of islet of langerhans (yellow arrows). (iv) AL200: Section of pancreas of STZ-induced diabetic rats treated with ALEx at 200 mg/kg body wt. portraying increased number of islet of langerhans with small proportions of beta cells (yellow arrows). (v) AL300: Pancreas of diabetic rats treated with 300 mg/kg body wt. ALEx depicting nearly normal islet of langerhans (yellow arrows). (vi) AL400: Sections of pancreas of diabetic treated rats with 400 mg/kg body wt. ALEx showing normal islet of langerhans with numerous beta cells (yellow arrows). (vii) GLP: Pancreatic section of diabetic rats treated with Glibenclamide showing normal pancreatic islet of langerhans with enhancement in the number of beta cells.

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