Figure 10
Effect of Albizia Lebbeck Benth. stem bark extract (ALEx) on histological profile of kidney in normal, STZ-induced diabetic untreated and STZ-induced diabetic treated wistar rats (Original magnification 40×, DXIT 1200 , Nikon, Japan). (i) NKALx: Heamatoxylin and eosin (H/E) stained sections of kidney of normal control rats showing normal glomeruli with normal baseline and tubules (yellow arrows). (ii) STK: Section of kidney of STZ-induced diabetic rats depicting destroyed glomeruli with fat deposition on baseline along with infiltration of lymphocytes (yellow arrows). (iii) KAL100: Kidney section of diabetic rats treated with ALEx at dose of 100 mg/kg body wt. portraying improved vasculature and glomeruli (yellow arrows). (iv) KAL200: Section of kidney of diabetic rats treated with 200 mg/kg body wt. of ALEx showing normal tubules along with virtually improved structure of glomeruli. (yellow arrows). (v) KAL300: Kidney section of diabetic treated rats with 300 mg/kg body wt of ALEx depicting nearly normal glomeruli (yellow arrows). (vi) KAL400: Section of kidney of diabetic rat received 400 mg/kg body wt. of ALEx showing normal glomeruli with no infiltration of lymphocytes (yellow arrows). (vii)KGLIB: Section of kidney of the rat supplemented with Glibenclamide showing normal glomeruli with improved structure of tubules (yellow arrows).