Figure 4

Inhibitory effect of OR on (A) NF-κB translocation into the nucleus and (B) IκBα phosphorylation. The cells were treated with LPS alone or with LPS and OR for 30 min (IκBα) or for 1 h (NF-κB). Protein expression in the cytosol or nucleus was determined by Western blot analysis. Data represent mean ± SE values of duplicate determinations from three independent experiments. *p < 0.01 and **p < 0.001 were calculated from comparisons the with LPS-stimulation value.