Xuan Bai Cheng Qi formula as an adjuvant treatment of acute exacerbation of chronic obstructive pulmonary disease of the syndrome type phlegm-heat obstructing the lungs: a multicenter, randomized, double-blind, placebo-controlled clinical trial

Table 6 Arterial blood gas analysis in Xuan Bai Cheng Qi and control groups before and after 10-day treatment

Variables^a	XBCQ^b			Control^b			Treatment effect^d(95% CI; P- value)
	Day 1 (Baseline)	Day 10 (End)	Mean D	Day 1 (Baseline)	Day 10 (End)	Mean D
PH
FAS (122,122)	7.41 (0.05)	7.41 (0.04)	0.01 (0.05)	7.42 (0.05)	7.42 (0.05)	-0.00 (0.05)	-0.00 (-0.01, 0.01; .894)
PPS (111,118)	7.41 (0.05)	7.41 (0.04)	0.00 (0.05)	7.42 (0.05)	7.42 (0.05)	-0.00 (0.05)	-0.00 (-0.01, 0.01; .794)
PaO₂
FAS (122,122)	75.56 (19.38)	85.69 (16.42)	13.13 (18.12)^c	71.47 (18.90)	80.49 (15.91)	9.01 (17.49)^c	4.75 (1.21, 8.28; .009)
PPS (111,118)	71.91 (19.28)	85.11 (16.59)	13.20 (18.50)^c	71.27 (19.08)	80.76 (15.96)	9.49 (17.31)^c	4.08 (0.04, 7.76; .030)
PaCO₂
FAS (122,122)	47.41 (10.04)	39.52 (11.55)	-7.89 (12.27)^c	39.52 (11.55)	41.45 (8.33)	-4.76 (8.97)^c	-2.48 (-4.53, -0.44; .018)
PPS (111,118)	46.46 (13.32)	38.93 (9.47)	-7.53 (11.49)^c	45.90 (11.82)	41.38 (8.41)	-4.52 (8.83)^c	-2.69 (-4.56, -0.81; .005)

Abbreviations: CI confidence interval, Mean D mean difference, PaO ₂ arterial partial pressure of oxygen, PaCO ₂ arterial partial carbon dioxide pressure, XBCQ Xuan Bai Cheng Qi.
^aFAS population was 122 in the XBCQ group and 122 in the control group; PPS population was 111 in the XBCQ group and 118 in the control group.
^bData presented as mean (SD).
^c P < .01: Change between pre - treatment and post - treatment (within group difference by paired t - test).
^dCovariance analysis estimate with 95% confidence interval for difference.

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