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Table 6 Arterial blood gas analysis in Xuan Bai Cheng Qi and control groups before and after 10-day treatment

From: Xuan Bai Cheng Qi formula as an adjuvant treatment of acute exacerbation of chronic obstructive pulmonary disease of the syndrome type phlegm-heat obstructing the lungs: a multicenter, randomized, double-blind, placebo-controlled clinical trial

Variablesa XBCQb Controlb Treatment effectd(95% CI; P- value)
  Day 1 (Baseline) Day 10 (End) Mean D Day 1 (Baseline) Day 10 (End) Mean D  
PH        
 FAS (122,122) 7.41 (0.05) 7.41 (0.04) 0.01 (0.05) 7.42 (0.05) 7.42 (0.05) -0.00 (0.05) -0.00 (-0.01, 0.01; .894)
 PPS (111,118) 7.41 (0.05) 7.41 (0.04) 0.00 (0.05) 7.42 (0.05) 7.42 (0.05) -0.00 (0.05) -0.00 (-0.01, 0.01; .794)
PaO2        
 FAS (122,122) 75.56 (19.38) 85.69 (16.42) 13.13 (18.12)c 71.47 (18.90) 80.49 (15.91) 9.01 (17.49)c 4.75 (1.21, 8.28; .009)
 PPS (111,118) 71.91 (19.28) 85.11 (16.59) 13.20 (18.50)c 71.27 (19.08) 80.76 (15.96) 9.49 (17.31)c 4.08 (0.04, 7.76; .030)
PaCO2        
 FAS (122,122) 47.41 (10.04) 39.52 (11.55) -7.89 (12.27)c 39.52 (11.55) 41.45 (8.33) -4.76 (8.97)c -2.48 (-4.53, -0.44; .018)
 PPS (111,118) 46.46 (13.32) 38.93 (9.47) -7.53 (11.49)c 45.90 (11.82) 41.38 (8.41) -4.52 (8.83)c -2.69 (-4.56, -0.81; .005)
  1. Abbreviations: CI confidence interval, Mean D mean difference, PaO 2 arterial partial pressure of oxygen, PaCO 2 arterial partial carbon dioxide pressure, XBCQ Xuan Bai Cheng Qi.
  2. aFAS population was 122 in the XBCQ group and 122 in the control group; PPS population was 111 in the XBCQ group and 118 in the control group.
  3. bData presented as mean (SD).
  4. c P < .01: Change between pre - treatment and post - treatment (within group difference by paired t - test).
  5. dCovariance analysis estimate with 95% confidence interval for difference.