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Table 4 Plasma metabolites detected in the sham-operated and model animals 45 days after the operation

From: Plasma metabonomics study on Chinese medicine syndrome evolution of heart failure rats caused by LAD ligation

Metabolic pathway RT (min) Metabolites Sham-operated (×109) Model (×109) P value
TAC 19.6 Citric acid 9.14 ± 7.010 1.91 ± 1.550 0.020
24.16 cAMP 0.44 ± 0.200 0.13 ± 0.236 0.040
Amino acid metabolism 8.01 Ethylbis(trimethylsilyl)amine 0.37 ± 0.124 0.69 ± 0.134 0.016
9.45 Alanine 0.67 ± 0.250 0.41 ± 0.148 0.015
10.15 Silanamine 2.34 ± 0.423 1.45 ± 0.537 0.041
10.91 L-Norvaline 2.14 ± 0.473 1.02 ± 0.909 0.047
11.67 L-Valine 0.29 ± 0.117 0.12 ± 0.032 0.014
12.00 Urea 4.775 ± 0.851 6.96 ± 1.963 0.086
13.17 Glycine 0.52 ± 0.154 0.24 ± 0.147 0.024
14.11 L-Serine 1.17 ± 0.511 1.67 ± 0.266▲▲ 0.001
16.15 L-Proline 0.51 ± 0.104 0.36 ± 0.047 0.036
Glucose metabolism 20.02 Ribitol 0.02 ± 0.053 0.35 ± 0.192▲▲ 0.002
22.52 Glucopyranoside 0.16 ± 0.046 0.07 ± 0.017 0.023
Fatty acid metabolism 8.73 Lactic acid 1.27 ± 0.102 1.69 ± 0.319 0.039
14.80 Butanoic acid 0.38 ± 0.080 0.52 ± 0.076 0.028
17.48 Dodecanoic acid 0.56 ± 0.811 0.37 ± 0.209 0.550
21.78 Hexadecanoic acid 2.45 ± 0.483 1.30 ± 0.707 0.023
23.19 Heneicosane 0.74 ± 0.256 0.06 ± 0.181 0.000
23.53 Octadecanoic acid 6.07 ± 0.927 4.28 ± 1.103 0.047
  28.32 Octadecatrienoic acid 1.25 ± 0.149 0.48 ± 0.309 0.002
  1. Note: increased significantly in model group, P < 0.05 compare with the Sham Group, ▲▲P < 0.01 compare with the Sham Group; decreased significantly in model group, P < 0.05 compare with the Sham Group, P < 0.01 compare with the Sham Group.