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Table 3 Plasma metabolites detected in the sham-operated and model animals 21 days after the operation

From: Plasma metabonomics study on Chinese medicine syndrome evolution of heart failure rats caused by LAD ligation

Metabolic pathway RT (min) Metabolites Sham-operated (×109) Model (×109) P value
TAC 19.60 Citric acid 1.92 ± 1.909 4.33 ± 1.240 0.026
24.18 cAMP 0.27 ± 0.092 0.10 ± 0.052 0.006
Amino acid metabolism 8.01 Ethylbis(trimethylsilyl)amine 0.79 ± 0.143 1.29 ± 0.437 0.048
9.60 Alanine 0.64 ± 0.037 1.08 ± 0.311 0.036
10.94 L-Norvaline 1.26 ± 0.616 2.28 ± 0.687 0.029
11.67 L-Valine 0.12 ± 0.032 0.29 ± 0.117 0.014
12.00 Urea 8.05 ± 1.569 13.41 ± 2.833▲▲ 0.008
13.17 Glycine 0.57 ± 0.247 0.27 ± 0.057 0.028
14.11 L-Serine 1.36 ± 0.301 1.76 ± 0.476▲▲ 0.001
16.94 L-Proline 0.57 ± 0.232 0.11 ± 0.027 0.005
Glucose metabolism 21.31 Glucopyranose 0.22 ± 0.050 20.64 ± 1.144▲▲ 0.000
22.52 Glucopyranoside 0.07 ± 0.017 0.16 ± 0.046 0.023
Fatty acid metabolism 8.77 Lactic acid 1.48 ± 0.036 2.62 ± 0.345▲▲ 0.000
9.25 Acetic acid 0.29 ± 0.073 0.47 ± 0.075▲▲ 0.004
14.80 Butanoic acid 0.39 ± 0.065 0.80 ± 0.212▲▲ 0.009
17.48 Dodecanoic acid 0.40 ± 0.050 1.02 ± 0.465 0.021
21.73 Hexadecanoic acid 1.87 ± 0.320 2.67 ± 0.398▲▲ 0.006
23.54 Octadecanoic acid 3.58 ± 0.965 5.49 ± 0.670▲▲ 0.004
25.99 Octadecatrienoic acid 0.07 ± 0.036 0.02 ± 0.117 0.022
  29.84 Monolinoleoylglycerol 1.13 ± 0.562 0.38 ± 0.201 0.040
  1. Note: increased significantly in model group, P < 0.05 compare with the Sham Group, ▲▲P < 0.01 compare with the Sham Group; decreased significantly in model group, P < 0.05 compare with the Sham Group, P < 0.01 compare with the Sham Group.