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Table 3 IC 50 , IC 100 and Selectivity Indices (SI) of the essential oil on O. ochengi

From: Anti-Onchocerca activity and phytochemical analysis of an essential oil from Cyperus articulatus L

Parameter Microfilariae Adult male worm Adult female worm Monkey kidney cells (LLC-MK2)
IC50 (μg/ml) 23.4 23.4 31.25 93.7
IC100 (μg/ml) 62.5 62.5 125 250
SI = IC50 MKC/IC50 worm 4.0 4.0 2.99 -
  1. SI (Selectivity Index) = IC50 on mammalian cells/ IC50 on parasite.