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Table 3 IC 50 , IC 100 and Selectivity Indices (SI) of the essential oil on O. ochengi

From: Anti-Onchocerca activity and phytochemical analysis of an essential oil from Cyperus articulatus L

Parameter

Microfilariae

Adult male worm

Adult female worm

Monkey kidney cells (LLC-MK2)

IC50 (μg/ml)

23.4

23.4

31.25

93.7

IC100 (μg/ml)

62.5

62.5

125

250

SI = IC50 MKC/IC50 worm

4.0

4.0

2.99

-

  1. SI (Selectivity Index) = IC50 on mammalian cells/ IC50 on parasite.