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Table 1 Plasma calcium (Ca +2 ), phosphorous (Pi), alkaline phosphatase (ALP), malondialdehyde (MDA), nitrates, tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) in SHAM-operated control (SHAM) rats, ovariectomized (OVX) rats, and Nigella sativa-supplemented ovariectomized (OVX-NS) rats

From: Nigella Sativa reverses osteoporosis in ovariectomized rats

  SHAM OVX OVX-NS
Ca+2 (mg/dl) 9.20 ± 0.68 7.86 ± 0.45a,b 9.09 ± 0.63
n = 10 n = 10 n = 10
Pi (mg/dl) 3.79 ± 0.24 4.12 ± 0.31 4.00 ± 0.35
n = 10 n = 10 n = 10
ALP (IU/liter) 58.10 ± 14.56 86.20 ± 9.37a 74.30 ± 10.24a
n = 10 n = 10 n = 10
NTx (nM BCE) 10 ± 1.28 28.69 ± 3.02a,b 10.84 ± 1.15
n = 10 n = 10 n = 10
MDA (μmol/l) 1.50 ± 0.19 1.92 ± 0.13a,b 1.71 ± 0.24
n = 10 n = 10 n = 10
Nitrates (μmol/l) 92.70 ± 20.77 142.20 ± 18.56a,b 75.50 ± 15.07
n = 10 n = 10 n = 10
TNF-α (pg/ml) 27.92 ± 2.68 87.62 ± 5.47a,b 36.55 ± 4.32a
n = 10 n = 10 n = 10
IL-6 (pg/ml) 18.87 ± 1.26 45.56 ± 4.72a,b 29.13 ± 4.60a
n = 10 n = 10 n = 10
  1. n is the number of observations.
  2. (a)is the significance calculated by Tukey test, P < 0.05 from SHAM-operated control group.
  3. (b)is the significance calculated by Tukey test, P < 0.05 from OVX-NS group.