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Table 3 Detection of HCV RNA in infected then treated Huh 7.5 cells a

From: Screening the anti infectivity potentials of native N- and C-lobes derived from the camel lactoferrin against hepatitis C virus

Protein

Protein conc. (mg/ml)

Calc. conc. (IU/ml)

Relative activity (%)

Control

Positive

53910

0.0 ± 0.01

Negative

0.0

100 ± 0.0

Lactoferrin (first dose)

0.25

26110

51.56 ± 0.038

0.5

12430

76.94 ± 0.02

0.75

2210

95.59 ± 0.045

1.0

0.0

100 ± 0.0

1.25

0.0

100 ± 0.0

N-lobe

0.25

520

99.03 ± 0.023

0.5

0.0

100 ± 0.0

0.75

0.0

100 ± 0.0

1.0

0.0

100 ± 0.0

1.25

0.0

100 ± 0.0

C-lobe (first dose)

0.25

40790

24.33 ± 0.032

0.5

24070

55.35 ± 0.046

0.75

13320

75.29 ± 0.033

1.0

1030

98.08 ± 0.041

1.25

0.0

100 ± 0.0

Lactoferrin (second dose)

0.25

6290

88.33 ± 0.012

0.5

580

98.92 ± 0.03

0.75

0.0

100 ± 0.0

C-lobe (second dose)

0.25

33950

37.02 ± 0.026

0.5

12370

77.05 ± 0.011

0.75

0.0

100 ± 0.0

 

1.0

0.0

100 ± 0.0

  1. aReal time PCR data for in vitro cLF, C- and N-lobe activity-treatment against HCV-infected Huh 7.5 cells. Huh 7.5 cells served as negative control, and infected Huh 7.5 cells with HCV served as positive control.