Table 4 Micronucleus test in mice following a single oral dose of Guibi-Tang (GBT) extract
Group | Vehicle control | GBT | GBT | GBT | Positive control (cyclophosphamide) |
|---|---|---|---|---|---|
Dose (mg/kg) | 0 | 500 | 1000 | 2000 | 70 |
MNPCE/2000PCEs (Mean ± S.D) | 0.33 ± 0.58 | 1.67 ± 1.15 | 1.00 ± 1.00 | 0.33 ± 0.58 | 62.33* ± 10.21 |
PCE/(PCE+NCE) (Mean ± S.D) | 0.48 ± 0.05 | 0.53 ± 0.07 | 0.50 ± 0.08 | 0.53 ± 0.05 | 0.46 ± 0.03 |
Number of animals | 3 | 3 | 3 | 3 | 3 |