The effects of Lycium chinense Miller root SFE on melanogenesis-related protein expression and signaling pathways. (A), (C). Western blotting of cellular proteins in B16F10 cells. (B), (D). The relative amounts of MITF, TRP-1, tyrosinase, TRP-2 and MC1R or phosphorylated proteins (p-JNK, p-ERK and p-p38) compared to the total GAPDH were calculated and analyzed using Multi Gauge 3.0 software, and the values represent the mean of triplicate experiments ± standard deviations. *p < 0.05.