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Table 1 The top five most commonly used herbal formulas for premenstrual syndrome (Nā€‰=ā€‰13,820)

From: Identifying Chinese herbal medicine for premenstrual syndrome: implications from a nationwide database

Herbal formula Constituents Indication of TCM syndrome Instances Dose (gm/day) Duration (day) Prevalence (%)
Jia-Wei-Xiao-Yao-San (JWXYS) Paeonia lactiflora Pall., Bupleurum chinense DC. DC., Atractylodes macrocephala Koidz., Poria cocos (Schw.) Wolf, Angelica sinensis (Oliv.) Diels., Mentha haplocalyx Briq., Glycyrrhiza uralensis Fisch., Zingiber officinale Rosc., Paeonia suffruticosa Andr., and Gardenia jasminoides Ellis. Liver and spleen blood deficiency with heat transforming, liver qi stagnation 5,185 4.87 6.4 37.5
Dang-Gui-Shao-Yao-San Angelica sinensis (Oliv.) Diels., Ligusticum chuanxiong Hort., Paeonia lactiflora Pall., Atractylodes macrocephala Koidz., Poria cocos (Schw.) Wolf, and Alisma plantago-aquatica L. var. Alisma orientale Samuels Liver blood deficiency and disharmony of Liver and Spleen 2,064 4.34 6.4 14.9
Gui-Zhi-Fu-Ling-Wan Cinnamomum cassia Blume, Poria cocos (Schw.) Wolf, Paeonia lactiflora Pall., Paeonia suffruticosa Andr., and Prunus persica (L.) Batsch (or Prunus davidiana (Carr.) Franch.) Blood stasis 1,245 3.87 6.3 9.0
Wen-Jing-Tang Evodia rutaecarpa (Juss.) Benth., (or Evodia rutaecarpa (Juss.) Benth. var. officinalis (Dode) Huang, Evodia rutaecarpa (Juss.) Benth. var. bodinieri (Dode) Huang), Cinnamomum cassia Blume, Angelica sinensis (Oliv.) Diels., Paeonia lactiflora Pall., Ligusticum chuanxiong Hort., Panax ginseng C. A. Meyer, Glycyrrhiza uralensis Fisch., Equus asinus L., Ophiopogon japonicus Ker-Gawl., Pinellia ternata (Thunb.) Breit, and Zingiber officinale Rosc. Blood stasis and deficient cold 1,120 4.25 6.3 8.1
Shao-Fu-Zhu-Yu-Tang Foeniculum vulgare Mill., Zingiber officinale Rosc., Cinnamomum cassia Blume, Angelica sinensis (Oliv.) Diels., Ligusticum chuanxiong Hort., Paeonia lactiflora Pall. or Peaonia veitchii Lynch, Trogopterus xanthipes Milne-Edwards or Pteromys volans L. Qi stagnation and blood stasis 994 3.97 6.2 7.2