Effect of JSOG-6 on bone loss in OVX mice. (A) Change in body weight 12 weeks after ovarietomy. (B) Effect of JSOG-6 on bone 3D microCT image of the distal femur in OVX mice. (C) Effect of JSOG-6 on the bone morphometric parameters BMD, BV/TV (%), and Tb.No (1/mm) as analyzed with micro-CT SkyScan CTAN software. Data represent the mean ± S.D. (n = 8). *P < 0.01 indicates statistically significant differences from the OVX mice group.