Inclusion criteria | Exclusion criteria |
---|---|
○ Healthy volunteers without clinical diagnosed diseases with relevant effect on the gastrointestinal system or on visceral motility | ○ Subject under prescription for medication for digestive symptoms such as anti-spasmodic, laxatives and anti-diarrheic drugs or other digestive auxiliaries |
○ Reduced bowel movements defined as an average of >1 and ≤ 3.5 stools per week for at least the previous 6 months | ○ Relevant history, presence of any medical disorder or intake of medication/dietary supplements, potentially interfering with this trial at screening |
○ BMI: 19-30 kg/m2 | ○ Subjects with stool frequency of ≤ 1 stool every 7 days or > 3.5 stools per week |
○ Gastrointestinal symptoms of at least 5 points | ○ Subjects not willing to avoid pre- and probiotics for the duration of the study |
○ Male or female | ○ Intake of antibiotics in the last 4 weeks and laxatives in the last 2 weeks |
○ Age ≥ 30 and ≤ 70 years | ○ Change of dietary habits within the 4 weeks prior to screening (for instance start of a diet high in fibers) |
○ Nonsmoker | ○ Pregnant subject or subject planning to become pregnant during the study; breast-feeding subject |
○ Written consent to participate in the study | ○ Subjects with history of drug, alcohol or other substances abuse, or other factors limiting their ability to co-operate during the study |
○ Able and willing to follow the study protocol procedures | ○ Participants anticipating a change in their lifestyle or physical activity levels since this may also influence the results |
○ Known food intolerance or allergy | |
○ Subject involved in any clinical or food study within the preceding month |