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Table 1 Cytotoxicity and antiviral activity of fractions obtained from the solvent partitionings of the methanol extract of L. speciosa leaves toward human rhinovirus-4 in HeLa cells using sulforhodamine B bioassay

From: Antiviral activity and possible mode of action of ellagic acid identified in Lagerstroemia speciosa leaves toward human rhinoviruses

Test material CC50(μg/mL) IC50(μg/mL) (±SD) TIa
Methanol extract 1036 82 ± 1.8d 12.6
Hexane-soluble fraction 1074 777 ± 5.8b 1.4
Ethyl acetate-soluble fraction 1675 71 ± 1.0d 23.5
Butanol-soluble fraction 1260 881 ± 8.7a 1.4
Water-soluble fraction 1409 607 ± 3.5c 2.3
  1. Means within a column followed by the same letter are not significantly different (P = 0.05, Bonferroni method).
  2. aTherapeutic index = CC50/IC50.