Figure 5

The flow chart of endothelium-dependent mediator of vasorelaxation by PVin rat thoracic. PV increase vessel diameter in an endotheliumdependent manner by stimulating production of nitric oxide. cGMP (cyclic guanosine monophosphate); GC (guanylyl cyclase); GTP (guanosine triphosphate); NO (nitric oxide); NOS (nitric oxide synthase).