TY - JOUR AU - Chang, Ming-Long AU - Chang, Jung-Su AU - Yu, Wen-Yu AU - Cheah, Khoot-Peng AU - Li, Joe-Sharg AU - Cheng, Hui-Wen AU - Hu, Chien-Ming PY - 2014 DA - 2014/05/07 TI - Polygonum viviparum L. induces vasorelaxation in the rat thoracic aorta via activation of nitric oxide synthase in endothelial cells JO - BMC Complementary and Alternative Medicine SP - 150 VL - 14 IS - 1 AB - In the past several decades, Polygonum viviparum L. (PV) was reported to have antibacterial, antiulcer, antioxidant, antitumor, anti-inflammatory, and antiarthritic properties. The anti-inflammatory pathway was recently elucidated through cytosolic nuclear factor E2-related factor 2 (Nrf2) activation and heme oxygenase (HO)-1 protein expression. PV is a perennial herb and widely distributed in high-elevation mountain regions, such as the Tibetan Plateau. In Tibetan traditional medicine, PV is usually used to boost the blood circulation to dissipate blood stasis. Therefore, this study focused on how PV improves the vascular circulation and acts on vascular tissues. SN - 1472-6882 UR - https://doi.org/10.1186/1472-6882-14-150 DO - 10.1186/1472-6882-14-150 ID - Chang2014 ER -