Table 2 Number of survived ICR mice following a single (acute toxicity) and multiple (subacute toxicity) oral dosing of plumbagin
From: Antimalarial activity of plumbagin in vitro and in animal models
Test group | Number of mice (survived/total) | |
|---|---|---|
Acute toxicity | Control (20% Tween-80) | 6/6 |
Plumbagin: 500 mg/kg body weight | 0/6 | |
Plumbagin: 200 mg/kg body weight | 4/6 | |
Plumbagin: 100 mg/kg body weight | 6/6 | |
Subacute toxicity | Control (Tween-80) | 6/6 |
Plumbagin: 100 mg/kg body weight | 0/6 | |
Plumbagin: 50 mg/kg body weight | 0/6 | |
Plumbagin: 25 mg/kg body weight | 6/6 |